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KMID : 0360419660020010031
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Korean Journal of Pharmacology
1966 Volume.2 No. 1 p.31 ~ p.40
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The influence of Calcium, Magnesium, Sodium and Potassium Ion on the Adenosintriphosphatase activity of heart and skeletal microsomal fraction of rabbits
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Abstract
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The microsomal fraction is isolated from rabbit heart and skeletal muscle. The fraction is found to contain the Na^(+)-and K^(+)-activated ATPase. The maximal ATPase activity is obtained in Na^(+) and K^(+) concentration of 100 mM.
Calcium itself stimulates the Na^(+)-and K^(+)-activated portion of ATPase in the presence of Mg^(++). However, calcium does not stimulate ATPase in the absence of Mg^(++).
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